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Index > Protein center > Zfp36l2(Gene name) > Mouse
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  • Zfp36l2 (Gene name),
  • Zinc finger protein 36, C3H1 type-like 2 (Protein name ),  TISD_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Zfp36l2(Brf2;Tis11d);
    Protein name:
    Zinc finger protein 36, C3H1 type-like 2(ZFP36-like 2);
    Alternative:
    Protein TIS11D;Butyrate response factor 2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Probable regulatory protein involved in regulating the response to growth factors. RNA-binding protein that binds to 5'UUAUUUAUUU-3' core sequence. Binds to the class II AU-rich element (ARE) in the 3'-UTR of target mRNAs and promotes their deadenylation and degradation.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    367
    Sequence:
    50:
    MLDKKAVGTP | VAAAPSSSFT | PGFLRRHSAS | NLHALAHPVP | SPGSCSPKFP | 
    100:
    GAPNGGGSSC | GPAGGGGLAS | YGQLKEPSGG | SGTALVTKES | KFRDRSFSEN | 
    150:
    GERSQHLLHL | QQQQKGGSGS | QINSTRYKTE | LCRPFEESGT | CKYGEKCQFA | 
    200:
    HGFHELRSLT | RHPKYKTELC | RTFHTIGFCP | YGPRCHFIHN | ADERRPAPSG | 
    250:
    GGGASGDLRA | FGARDALHLG | FAREPRPKLH | HSLSFSGFPS | GHHQPPGGLE | 
    300:
    SPLLLDSPTS | RTPPPPSSSA | SSCSSSASSC | SSASAASTPS | GAPTCCATAA | 
    350:
    AAALLYGPGG | AEDLLSPGAP | CASCSSSGAN | NAFAFGPELS | SLITPLAIQT | 
    367:
    HNFAAAPPPT | TATSSRA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    SMR:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse ZFP36-like 2
    Cat.:
    E5956h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse ZFP36-like 2
    Cat.:
    E5956m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse ZFP36-like 2
    Cat.:
    U5956m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse ZFP36-like 2
    Cat.:
    U5956h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse ZFP36-like 2
    Cat.:
    P5956Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse ZFP36-like 2
    Cat.:
    P5956Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse ZFP36-like 2
    Monoclonal Antibody for Mouse ZFP36-like 2
    Protein for Mouse ZFP36-like 2
    Protein for Mouse ZFP36-like 2

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      strain: NOD.
      tissue: Head.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    4. 4.
      "Structure and expression of two mitogen inducible genes."
      Fletcher B.S.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-50
    5. 5.
      "The TIS11 primary response gene is a member of a gene family that encodes proteins with a highly conserved sequence containing an unusual Cys-His repeat."
      Varnum B.C. , Ma Q. , Chi T. , Fletcher B.S. , Herschman H.R.
      Mol. Cell. Biol.11:1754-1758(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 25-396
      strain: BALB/c.
    6. 6.
      "Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling."
      Phillips R.S. , Ramos S.B. , Blackshear P.J.
      J. Biol. Chem.277:11606-11613(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    7. 7.
      "The CCCH tandem zinc-finger protein Zfp36l2 is crucial for female fertility and early embryonic development."
      Ramos S.B. , Stumpo D.J. , Kennington E.A. , Phillips R.S. , Bock C.B. , Ribeiro-Neto F. , Blackshear P.J.
      Development131:4883-4893(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
    8. 8.
      "Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis."
      Stumpo D.J. , Broxmeyer H.E. , Ward T. , Cooper S. , Hangoc G. , Chung Y.J. , Shelley W.C. , Richfield E.K. , Ray M.K. , Yoder M.C. , Aplan P.D. , Blackshear P.J.
      Blood114:2401-2410(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
    9. 9.
      "Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia."
      Hodson D.J. , Janas M.L. , Galloway A. , Bell S.E. , Andrews S. , Li C.M. , Pannell R. , Siebel C.W. , MacDonald H.R. , De Keersmaecker K. , Ferrando A.A. , Grutz G. , Turner M.
      Nat. Immunol.11:717-724(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
    10. 10.
      "Characterization of DeltaN-Zfp36l2 mutant associated with arrest of early embryonic development and female infertility."
      Ramos S.B.
      J. Biol. Chem.287:13116-13127(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    11. 11.
      "ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors."
      Zhang L. , Prak L. , Rayon-Estrada V. , Thiru P. , Flygare J. , Lim B. , Lodish H.F.
      Nature499:92-96(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DEVELOPMENTAL STAGE;INDUCTION;RNA-BINDING
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